Colorectal cancer patients with distant metastases often undergo multiple procedures, such as repeat hepatectomy and lung resection for lung metastasis, in addition to primary lesion resection; therefore, minimally invasive surgery with small incisions and less postoperative adhesions is beneficial for these patients. However, both technical and oncological limitations of a laparoscopic approach and the selection criteria for surgical procedures, regardless of an open or laparoscopic approach, should be carefully considered, to properly perform laparoscopic hepatectomy for colorectal liver metastases (CRLMs). For instance, multiple partial resections are often better for multiple CRLMs than a simple major hepatectomy in which more than half of the main vessels (Glissonean branches and drainage veins) are lost, because the options for subsequent hepatectomy are increased with parenchymal regeneration around preserved vessels. However, the cutting surface is often very close to the tumor surface in this type of surgery. Moreover, it is difficult to secure a narrow margin using a laparoscopic approach because of limitations associated with less tactile sensation and potential disorientation. In addition, long operative times limit the laparoscopic approach. Furthermore, it is important to avoid destroying hilar structures to reduce the difficulty of subsequent hepatectomy. Accordingly, continuous exposure of Glissonean branches from the hepatic hilum, which becomes easier with the advantage of a laparoscopic caudal view, should not be employed as much as possible. A laparoscopic approach should be selected according to the surgeon’s skill level, indications for the procedure, and the limitations.