The number of liver resection performed for metastatic cancer has increased over the past few decades. Liver resection for liver metastasis of colorectal cancer is now considered the standard of treatment for resectable patients with isolated hepatic disease, acceptable performance status and without extrahepatic metastasis.
Technical modifications for liver resection, more improved patient selection, and advances in perioperative care have made liver resection safer and more feasible. So, there is an increasing trend toward performing liver resection in the setting of metastatic disease. However, the indications for resection of non-colorectal, non-neuroendocrine origin liver metastases are not as clearly defined.
Because of improvements in perioperative outcomes as well as more effective chemotherapeutic agents, resection of colorectal liver metastasis is now well established, with most centers reporting a 5-year survival following surgery ranging from 40% to 58%. In contrast, surgical resection of liver metastasis secondary to other of non-colorectal, non-neuroendocrine primary tumors is more controversial. Although some groups have reported surgical resection of a wide variety of histological subtypes, the data for resection of non-colorectal, non-neuroendocrine metastatic disease to the liver are not well established, and the available data are still somewhat limited.
In this session, I will talk about an overview of the surgical management of patients with of non-colorectal, non-neuroendocrine liver metastasis.