HBP SURGERY WEEK 2018

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[Poster - Pancreas Disease/Surgery]

[P131] Effects of nutritional status on functionality and clinical outcomes in elderly patients with periampullary neoplasm
Eunjung KIM, Jin-Young JANG, Youngmin HAN, Jaeri KIM, Wooil KWON, Zhao JIYONG, Sun-Whe KIM
Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea, China

Introduction : The aged society with longer life expectancies, more pancreatic procedures will be taken in the elderly individuals. Although malnutrition is a factor affecting morbidity, costs of healthcare, impaired functions in the elderly, it often remains undetected or unaddressed before and after surgery. The aim was to investigate functional outcomes and QOL according to the nutritional status in elderly patients with periampullary neoplasm for 1 year, and to evaluate clinical outcomes according to nutritional status after PD.



Methods : Data were prospectively collected from 154 elderly patients (≥ 65) between 2008 and 2014. Nutritional status was evaluated with Mini Nutrition Assessment (MNA). Nutritional status was classified as well-nourished (MNA ≥ 22), at-risk-of malnutrition (MNA 15.5-21.5), and malnourished (MNA ≤ 15). Five function scales (physical, cognitive, emotional, social, role) and QOL were measured the EORTC QLQ-C30 questionnaires. All data were collected serially for 1 year.



Results : The mean age was 71 years and advanced age (≥ 75) was significantly higher complication rates and longer hospital stay (p=.047, p=.043). However, there was no significant difference in clinical outcomes regarding nutritional status. The prevalence of preoperative malnutrition was 27.3%, and more than half of all patients were at-risk-of malnutrition. Even after 1 year of surgery, over 70% of all elderly patients were at-risk-of malnutrition or malnourished. Preoperatively, malnourished group performed significantly worse than other groups in the physical (p<.001), emotional (p=.031), social (p=.002), role function (p<.001) and QOL (p<.001), but not in the cognitive function (p=.127). In addition, the physical, role function scores and QOL of the malnourished group were significantly lower overall periods compared to the other groups.



Conclusions : Malnourished elderly with periampullary neoplasm are more likely to suffer from long-term physical, role function impairment and low QOL. Vigorous efforts are needed to improve nutritional status before and after surgery, which ultimately may improve functional outcomes and QOL.

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Poster / Exhibition Hall and Lobby(2F) 1/1/1970 9:00 AM - 9:00 AM