Introduction : In this study our purpose is analysis of retrospective patients with I-III stages which went to the surgery and postoperative chemo – and radiotherapy in Kazakh Scientific Research Institute of Oncology and Radiology.

Methods : Totally 64 patients between 2009 and 2016 underwent surgical treatment of pancreatic cancer and follow-up. Which of them: pancreatoduodenal resection was performed in 37 patients, corpocaudal resection in 12 patients, distal pancreas resection in 12 patients, total pancreatectomy performed to 3 patients. Resequence in pancreatic head cancer was 25.5%, with carcinoma of the body and tail - 10.1%.

Results : Postoperative mortality for pancreatoduodenal resection was 8.7% (in the last 5 years - 3.5%), distal resection was 13.3%. The average life expectancy after pancreatoduodenal resection was 17.4 months, pancreatectomy - 8 months, distal subtotal pancreas resection - 11.2 months. Three years after pancreatoduodenal resections, 14.7% lived, and the 5-year survival rate was 4.4%. After palliative surgery, the average life expectancy was 5.2 months. The best long-term results were observed when applying a complex and combined treatment. In distal pancreas resection postoperative use of SBRT/IMRT radiation therapy or induced chemotherapy, give almost same results.

Conclusions : In this way, improvement of the treatment results of pancreatic cancer is possible with early diagnosis and applying of complex and combined treatment. Patients should be classified and treated with a multidisciplinary approach at specialized centers.