Detailed Abstract
[Poster - Pancreas Disease/Surgery]
[P111] Long term outcomes and prognostic factors of resected pancreatic neuroendocrine tumors
Hyung Jun KWON1, Sang Geol KIM1, Young Seok HAN2, Heontak HA2, Jae Min CHUN2, Yoon Jin HWANG1
1Surgery, Kyungpook National University Chilgok Hospital, Kyungpook National University School of Medicine, Korea
2Surgery, Kyungpook National University Hospital, Kyungpook National University School of Medicine, Korea, Korea
Introduction : Pancreatic neuroendocrine tumors (PNET) are a rare subgroup of tumors. For PNETs, the predictive factors for survival and prognosis are not well known. The aim of the present study was to investigated the clinicopathological and prognosis of the patients with resected pancreatic neuroendocrine tumors (PNET).
Methods : 42 patients with PNET underwent surgical treatment from April 1992 to June 2017. Data regarding the clinicopathologic factors of these patients were collected retrospectively. Factors influencing the prognosis of advanced gallbladder cancer after resection were analyzed by univariate and multivariate analysis.
Results : The patients comprised of 18 men and 24 women. The mean age of the patients was 53.98?2.75 years. Nine cases (21.4%) were functional tumors and 33 cases (78.6%) were non-functional tumors. The mean tumor size was 2.99?.08 cm. The most common location was tail (38.1%) and head (35.7%), followed body (21.4%), and body & tail(4.8%) in pancreas. The differences in the disease specific survival time as grading system based on Ki-67 and mitotic count were only statistically significant (P=0.015). The 5-year disease specific survival rates of patients with Grade 3 tumor was 0%. The T category (P=0.115), N category (P=0.299), TNM staging system (P=0.458), lymphovascular invasion (P=0.479), and perineural invasion (0.527) were not statistically significant factors.
Conclusions : : Patient with grade 3 PNET have worse postoperative prognosis. Therefore, we need careful monitoring after surgery.
Methods : 42 patients with PNET underwent surgical treatment from April 1992 to June 2017. Data regarding the clinicopathologic factors of these patients were collected retrospectively. Factors influencing the prognosis of advanced gallbladder cancer after resection were analyzed by univariate and multivariate analysis.
Results : The patients comprised of 18 men and 24 women. The mean age of the patients was 53.98?2.75 years. Nine cases (21.4%) were functional tumors and 33 cases (78.6%) were non-functional tumors. The mean tumor size was 2.99?.08 cm. The most common location was tail (38.1%) and head (35.7%), followed body (21.4%), and body & tail(4.8%) in pancreas. The differences in the disease specific survival time as grading system based on Ki-67 and mitotic count were only statistically significant (P=0.015). The 5-year disease specific survival rates of patients with Grade 3 tumor was 0%. The T category (P=0.115), N category (P=0.299), TNM staging system (P=0.458), lymphovascular invasion (P=0.479), and perineural invasion (0.527) were not statistically significant factors.
Conclusions : : Patient with grade 3 PNET have worse postoperative prognosis. Therefore, we need careful monitoring after surgery.
SESSION
Poster
Poster / Exhibition Hall and Lobby(2F) 1/1/1970 9:00 AM - 9:00 AM