Introduction : Metastatic cancer to the pancreas is rare and accounts for 2%~5% of all pancreatic malignancies, metastasis from renal cell carcinoma is the most frequent. Pancreatic metastasis from renal cell carcinoma (RCC) can be only site of metastasis and can be surgically resectable. In this study, we report six cases of metastatic rcc of the pancreas which underwent surgical treatment.

Methods : Between March 2016 to August 2017, six patients (three men and three women of mean age 61.5?.7 years) underwent pancreatectomy for RCC metastasis. We retrospectively reviewed clinicopathological data on those patients.

Results : Pancreas metaststasis occurred metachronously in all patients, with a mean interval from primary renal cell carcinoma of 5.8?.0 years. The mean length of hospital stay was 14.8?.3 day. In-hospital mortality did not occur. Histological examination confirmed the location of a secondary RCC in all patients. Among the six patients, two patients have multiple lesions of the pancreas and 4 patients were a solitary lesion. Median follow-up after pancreatectomy was 8.5 months (5-35months). Four patients were alive with no evidence of disease at 2, 4, 5, and 6 months after resection. Two patients had recurrent disease but were still alive at 17 and 34 months after resection.

Conclusions : Single localization of RCC metastasis to the pancreas is rare and it has a slow growing pattern. A hypervascular solid pancreatic tumor, in a patient who has previously undergone nephrectomy for RCC should be considered as suspicious metastasis. In selected patients, standard pancreatic resection might be an option an can be associated good results.