Introduction : Even the precise mechanism of fatty liver after pancreatectomy have remained unclear, fatty liver was associated with pancreatic exocrine and endocrine dysfunction. The aim of this study was to identify the oncologic impact of fatty liver after pancreaticoduodenectomy (PD) in patients with pancreatic ductal adenocarcinoma.

Methods : Clinicopathologic data and postoperative fatty liver changes for the patients who underwent PD with pancreatic head cancer were retrospectively reviewed. Hepatic attenuation values were measured on four random points of the liver with non-enhanced computed tomography (CT).

Results : Among 123 patients without preoperative fatty liver, 31 patients (22.3%, group A) developed new onset fatty liver in early postoperative follow-up period. Group B was defined as no fatty liver. There was no difference in terms of age, gender, tumor size, TNM stage, complication, and adjuvant chemotherapy between two groups. Preoperative and postoperative controlling nutritional status (CONUT), as calculated from serum albumin, total cholesterol concentration, and total lymphocyte count, score were significant different in each group (Group A, 2.8?.8 vs. 4.4?.4, p

Conclusions : Postoperative new onset fatty liver did not show adverse oncologic impact in resected pancreatic head cancer.