Introduction : Our aim is to provide evidence for a minimally invasive approach for T2 gallbladder (GB) cancer, comparing feasibility and oncologic outcome and determining optimal extent of lymph node dissection.

Methods : We analyzed 183 patients T2 GB cancer who underwent radical cholecystectomy for curative purporse from January 2006 to December 2017.

Results : The open surgery group was higher in the operation time, the estimated blood loss, the transfusion, and the preoperative serum CA 19-9 compared to minimally invaisive surgery group. The patients who underwent extended lymph node dissection (paraaortic lymph node dissection addition to regional lymph node dissection) were statistically significant in the open group. ( 70.4% vs 31% , p

Conclusions : In T2 GB cancer, number of metastatic lymph nodes and N stage affect the oncologic oocome, and paraaortic node dissection may improve overall survival.