Detailed Abstract
[BP Oral Presentation 2 - Biliary Disease/Surgery]
[BP OP 2-6] Achieving margin negative resection - doing less is justified: Oncological outcomes of wedge excision of liver in gall bladder cancer (GBC) surgery
Krunal KHOBRAGADE, Shraddha PATKAR, Vijayraj PATIL, Sagar KURUNKAR, Mahesh GOEL
Department of Surgical Oncology, Tata Memorial Hospaital, Parel, India, India
Introduction : The extent of liver resection for gall bladder cancer (GBC) is still debated. We evaluated the post-operative and oncological outcomes of patients who underwent liver wedge excision.
Methods : Patients who underwent radical cholecystectomy (with a liver wedge excision of 2.5-3 centimetres) from June 2010 to December 2015 were retrospectively analysed.
Results : 97 cases of primary GBC out of 558 patients undergoing surgery for GBC were selected. Majority of our patients had stage III disease (52 %). At a median follow up of 29 months, 65.9 % of patients were disease free where as 13.4% were alive with disease. 2.1 % died in postoperative period, 12.3% patients died of disease and 6.1% died of unrelated causes.9 patients had loco- regional recurrence and 16 failed at distant sites. Only one patient recurred in the gall bladder bed. 3-year overall survival of stage II was 85 % and of stage III was 60 %.
Conclusions : Surgical outcomes of radical cholecystectomy with wedge resection of the liver at our centre, parallels published international literature. With low morbidity and mortality, it emphasizes oncological equivalence of liver wedge resection as compared to formal segment IVb/V excision, provided a margin negative resection is achieved
Methods : Patients who underwent radical cholecystectomy (with a liver wedge excision of 2.5-3 centimetres) from June 2010 to December 2015 were retrospectively analysed.
Results : 97 cases of primary GBC out of 558 patients undergoing surgery for GBC were selected. Majority of our patients had stage III disease (52 %). At a median follow up of 29 months, 65.9 % of patients were disease free where as 13.4% were alive with disease. 2.1 % died in postoperative period, 12.3% patients died of disease and 6.1% died of unrelated causes.9 patients had loco- regional recurrence and 16 failed at distant sites. Only one patient recurred in the gall bladder bed. 3-year overall survival of stage II was 85 % and of stage III was 60 %.
Conclusions : Surgical outcomes of radical cholecystectomy with wedge resection of the liver at our centre, parallels published international literature. With low morbidity and mortality, it emphasizes oncological equivalence of liver wedge resection as compared to formal segment IVb/V excision, provided a margin negative resection is achieved
SESSION
BP Oral Presentation 2
Room C 3/30/2018 3:20 PM - 4:10 PM